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Nevertheless, it is recognized that DNIs may influence health outcomes in vulnerable populations, such as elderly, obese, critically ill, transplant recipients, patients receiving enteral or parenteral nutrition, chronically diseased patients, or patients under polypharmacy [44]

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The study population characteristics were: median age of 64 years (range: 34 to 84), 49% age 65 years or older, 59% male, 94% White and 3% Asian, and 18% with history of brain metastases at baseline

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